John F Alcorn Selected Research

Small Interfering RNA (siRNA)

6/2019

A dual controllability analysis of influenza virus-host protein-protein interaction networks for antiviral drug target discovery.

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John F Alcorn Research Topics

Disease

40	Infections 01/2024 - 12/2008
30	Human Influenza (Influenza) 01/2024 - 10/2009
24	Inflammation (Inflammations) 12/2023 - 11/2007
20	Asthma (Bronchial Asthma) 01/2020 - 11/2007
14	Pneumonia (Pneumonitis) 12/2023 - 04/2009
9	Lung Injury 01/2024 - 10/2010
6	Respiratory Hypersensitivity 02/2016 - 11/2007
5	Cystic Fibrosis (Mucoviscidosis) 02/2024 - 07/2004
5	Superinfection 01/2024 - 01/2018
5	Fibrosis (Cirrhosis) 01/2020 - 11/2007
4	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2020 - 11/2007
4	Acute Lung Injury 01/2019 - 10/2009
4	Coinfection 07/2015 - 02/2011
3	Bacterial Pneumonia 01/2024 - 10/2009
3	Communicable Diseases (Infectious Diseases) 01/2024 - 12/2013
3	Chronic Obstructive Pulmonary Disease (COPD) 01/2019 - 01/2010
3	Airway Remodeling 05/2014 - 11/2007
2	Virus Diseases (Viral Diseases) 12/2023 - 10/2009
2	Emphysema 01/2020 - 01/2011
2	Bacterial Infections (Bacterial Infection) 12/2019 - 01/2017
2	Eosinophilia 02/2016 - 11/2007
2	Metaplasia 02/2016 - 05/2008
2	Staphylococcal Pneumonia 02/2015 - 03/2014
2	Allergic Bronchopulmonary Aspergillosis 01/2015 - 09/2010
2	Lung Diseases (Lung Disease) 04/2014 - 04/2009
2	Weight Loss (Weight Reduction) 01/2013 - 10/2009
1	Necrosis 02/2024
1	Neoplasms (Cancer) 02/2024
1	Diarrhea 01/2024
1	Malnutrition (Nutritional Deficiencies) 01/2024
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2024
1	COVID-19 03/2023
1	Lymphocytic Choriomeningitis 01/2023
1	Cytokine Release Syndrome 01/2023

Drug/Important Bio-Agent (IBA)

27	CytokinesIBA 02/2024 - 11/2007
17	Interleukin-17 (Interleukin 17)IBA 12/2019 - 09/2008
11	Interleukin-22 (IL-22)IBA 02/2024 - 09/2008
10	Proteins (Proteins, Gene)FDA Link 01/2024 - 10/2010
7	AntigensIBA 10/2016 - 05/2008
6	ChemokinesIBA 01/2020 - 01/2011
5	Antiviral Agents (Antivirals)IBA 12/2023 - 01/2012
5	Biomarkers (Surrogate Marker)IBA 03/2023 - 01/2013
4	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2020 - 11/2007
4	NF-kappa B (NF-kB)IBA 06/2019 - 05/2008
4	SteroidsIBA 02/2016 - 09/2008
4	OvalbuminIBA 05/2013 - 01/2010
3	LigandsIBA 02/2024 - 10/2009
3	Influenza Vaccines (Influenza Vaccine)FDA Link 03/2023 - 12/2017
3	InterferonsIBA 01/2020 - 01/2019
3	Mitogen-Activated Protein Kinase 8IBA 01/2020 - 04/2009
3	VaccinesIBA 01/2020 - 01/2014
3	Interleukin-33IBA 01/2019 - 09/2015
3	Interleukin-13IBA 01/2019 - 09/2015
3	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2019 - 01/2012
3	Interleukin-6 (Interleukin 6)IBA 01/2019 - 09/2008
3	InflammasomesIBA 01/2018 - 05/2013
3	Interferon Type IIBA 01/2018 - 07/2015
3	Vitamin D FDA LinkGeneric 01/2018 - 01/2012
3	Antimicrobial PeptidesIBA 07/2015 - 03/2014
3	Nitrogen DioxideIBA 05/2013 - 10/2010
3	Transforming Growth Factor beta1 (TGF beta 1)IBA 04/2009 - 11/2007
2	ZincIBA 01/2024 - 03/2013
2	Immunoglobulin G (IgG)IBA 06/2023 - 10/2016
2	Interleukin-10 (Interleukin 10)IBA 03/2023 - 02/2015
2	Virulence Factors (Pathogenicity Factors)IBA 10/2022 - 01/2019
2	Protein Disulfide-IsomerasesIBA 01/2022 - 01/2019
2	Interferon LambdaIBA 01/2021 - 01/2019
2	JNK Mitogen-Activated Protein KinasesIBA 01/2020 - 05/2012
2	Phosphotransferases (Kinase)IBA 01/2020 - 05/2014
2	SmokeIBA 01/2020 - 01/2011
2	Bleomycin (Blenoxane)FDA LinkGeneric 01/2020 - 04/2009
2	interleukin-22 receptor (IL-22R)IBA 11/2019 - 04/2013
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2018
2	Lipocalin-2IBA 01/2019 - 01/2012
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2018 - 01/2013
2	MicroRNAs (MicroRNA)IBA 04/2017 - 05/2014
2	Immunoglobulin E (IgE)IBA 01/2017 - 10/2016
2	AllergensIBA 10/2016 - 10/2012
2	Fatty Acids (Saturated Fatty Acids)IBA 09/2015 - 04/2014
2	Receptor for Advanced Glycation End ProductsIBA 09/2015 - 10/2012
2	Cholecalciferol (Vitamin D3)FDA Link 01/2015 - 09/2010
2	Oxidants (Oxidizing Agents)IBA 05/2013 - 10/2010
1	B-Cell Activating FactorIBA 02/2024
1	ivacaftor drug combination tezacaftorIBA 02/2024
1	Interleukin-8 (Interleukin 8)IBA 02/2024
1	elexacaftorIBA 02/2024
1	Interleukin-12 Subunit p40IBA 02/2024
1	Surface-Active Agents (Surfactants)IBA 01/2024
1	SecretoglobinsIBA 01/2024
1	Protein CIBA 01/2024
1	Sirolimus (Rapamycin)FDA Link 12/2023
1	Mechanistic Target of Rapamycin Complex 1IBA 12/2023
1	TOR Serine-Threonine KinasesIBA 12/2023
1	Immunoglobulin M (IgM)IBA 06/2023
1	Immunoglobulin A (IgA)IBA 06/2023
1	InterleukinsIBA 03/2023
1	Interferon-gamma (Interferon, gamma)IBA 01/2023

Therapy/Procedure

9	Therapeutics 02/2024 - 01/2010
2	Intranasal Administration 05/2014 - 05/2013
1	Intravenous Administration 01/2023